Population geneticist Luigi Luca Cavalli Sforza
Luigi Luca Cavalli-Sforza (Italian: [luˈiːdʒi ˈluːka kaˈvalli ˈsfɔrtsa]; 25 January 1922 – 31 August 2018) was an Italian American population geneticist, who has lectured at Stanford University.
Cavalli-Sforza initiated a new field of research by combining the concrete findings of demography with a newly-available analysis of blood groups in an actual human population. He also studied the connections between migration patterns and blood groups.
Writing in the mid-1960s with another genetics student of Ronald A. Fisher, Anthony W. F. Edwards, Cavalli-Sforza pioneered statistical methods for estimating evolutionary trees (phylogenies); to estimate evolutionary trees, they used maximum likelihood estimation. Edwards and Cavalli-Sforza wrote about trees of populations within the human species, where genetic differences are affected both by treelike patterns of historical separation of populations and by spread of genes among populations by migration and admixture. In later papers, Cavalli-Sforza has written about the effects of both divergence and migration on human gene frequencies.
While Cavalli-Sforza is best known for his work in genetics, he also, in collaboration with Marcus Feldman and others, initiated the sub-discipline of cultural anthropology known alternatively as coevolution, gene-culture coevolution, cultural transmission theory or dual inheritance theory. The publication Cultural Transmission and Evolution: A Quantitative Approach (1981) made use of models from population genetics and infectious disease epidemiology to investigate the transmission of culturally transmitted units. This line of inquiry initiated research into the correlation of patterns of genetic and cultural dispersion.
Cavalli-Sforza has summed up his work for laymen in five topics covered in Genes, Peoples, and Languages.[2] According to an article published in The Economist, the work of Cavalli-Sforza "challenges the assumption that there are significant genetic differences between human races, and indeed, the idea that 'race' has any useful biological meaning at all". The book illustrates both the problems of constructing a general "hereditary tree" for the entire human race, and some mechanisms and data analysis methods to greatly reduce these problems, thus constructing a fascinating hypothesis of the recent 150,000 years of human expansion, migration, and human diversity formation.[3] In the book Cavalli-Sforza asserts that Europeans are, in their ancestry, about two-thirds Asian and one-third African.[4]
Cavalli-Sforza's The History and Geography of Human Genes[5] (1994 with Paolo Menozzi and Alberto Piazza) is a standard reference on human genetic variation. Cavalli-Sforza also wrote The Great Human Diasporas: The History of Diversity and Evolution (together with his son Francesco).
Earlier, in the 1970s, he and Walter Bodmer wrote what was the standard textbook on modern human genetics, and was also a basic reference for population genetics more generally, as the field was at the time, The Genetics of Human Populations. WHFreeman, 1971. The two, with Bodmer as first author, later wrote another more basic text, Genetics, Evolution, and Man WHFreeman, 1976. Along with his 1994 book these are essentially classical presentations of human genetics before the genomics era began providing very much more detailed data.
Cavalli-Sforza's proposed Human Genome Diversity Project to gather further genetic data from populations around the world did not advance as he originally envisioned the project.
Cavalli-Sforza has conducted several studies of how language differences may serve as barriers to gene flow between adjacent human populations. His studies of human migration have tested hypotheses of linguists Merritt Ruhlen and Joseph Greenberg about language "superfamilies." The hypothesized superfamilies are controversial among other linguists.[7]
https://en.wikipedia.org/wiki/Luigi_Luca_Cavalli-Sforza
Luigi Luca Cavalli-Sforza (Italian: [luˈiːdʒi ˈluːka kaˈvalli ˈsfɔrtsa]; 25 January 1922 – 31 August 2018) was an Italian American population geneticist, who has lectured at Stanford University.
Cavalli-Sforza initiated a new field of research by combining the concrete findings of demography with a newly-available analysis of blood groups in an actual human population. He also studied the connections between migration patterns and blood groups.
Writing in the mid-1960s with another genetics student of Ronald A. Fisher, Anthony W. F. Edwards, Cavalli-Sforza pioneered statistical methods for estimating evolutionary trees (phylogenies); to estimate evolutionary trees, they used maximum likelihood estimation. Edwards and Cavalli-Sforza wrote about trees of populations within the human species, where genetic differences are affected both by treelike patterns of historical separation of populations and by spread of genes among populations by migration and admixture. In later papers, Cavalli-Sforza has written about the effects of both divergence and migration on human gene frequencies.
While Cavalli-Sforza is best known for his work in genetics, he also, in collaboration with Marcus Feldman and others, initiated the sub-discipline of cultural anthropology known alternatively as coevolution, gene-culture coevolution, cultural transmission theory or dual inheritance theory. The publication Cultural Transmission and Evolution: A Quantitative Approach (1981) made use of models from population genetics and infectious disease epidemiology to investigate the transmission of culturally transmitted units. This line of inquiry initiated research into the correlation of patterns of genetic and cultural dispersion.
Cavalli-Sforza has summed up his work for laymen in five topics covered in Genes, Peoples, and Languages.[2] According to an article published in The Economist, the work of Cavalli-Sforza "challenges the assumption that there are significant genetic differences between human races, and indeed, the idea that 'race' has any useful biological meaning at all". The book illustrates both the problems of constructing a general "hereditary tree" for the entire human race, and some mechanisms and data analysis methods to greatly reduce these problems, thus constructing a fascinating hypothesis of the recent 150,000 years of human expansion, migration, and human diversity formation.[3] In the book Cavalli-Sforza asserts that Europeans are, in their ancestry, about two-thirds Asian and one-third African.[4]
Cavalli-Sforza's The History and Geography of Human Genes[5] (1994 with Paolo Menozzi and Alberto Piazza) is a standard reference on human genetic variation. Cavalli-Sforza also wrote The Great Human Diasporas: The History of Diversity and Evolution (together with his son Francesco).
Earlier, in the 1970s, he and Walter Bodmer wrote what was the standard textbook on modern human genetics, and was also a basic reference for population genetics more generally, as the field was at the time, The Genetics of Human Populations. WHFreeman, 1971. The two, with Bodmer as first author, later wrote another more basic text, Genetics, Evolution, and Man WHFreeman, 1976. Along with his 1994 book these are essentially classical presentations of human genetics before the genomics era began providing very much more detailed data.
Cavalli-Sforza's proposed Human Genome Diversity Project to gather further genetic data from populations around the world did not advance as he originally envisioned the project.
Cavalli-Sforza has conducted several studies of how language differences may serve as barriers to gene flow between adjacent human populations. His studies of human migration have tested hypotheses of linguists Merritt Ruhlen and Joseph Greenberg about language "superfamilies." The hypothesized superfamilies are controversial among other linguists.[7]
https://en.wikipedia.org/wiki/Luigi_Luca_Cavalli-Sforza
The ideal subject of totalitarian rule is not the convinced Nazi or the dedicated Communist but instead the people for whom the distinction between fact and fiction, true and false, no longer exists -- Hannah Arendt.